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Effect of Product Characteristics on the Abuse Liability of Nicotine Pouches

RecruitingNAAges 21 Years - 35 YearsAllEmory University
NCT07165808 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this study is to assess the effects of nicotine concentration and its interplay with pH on sensory experience, product appeal, and abuse liability of NPs among young adults NP users. Primary objective is to assess the effect of variation in nicotine concentration in nicotine pouches (NPs) and its interaction effect with pH level on three proximal outcomes of relevance to regulation: (1) sensory experience, (2) product appeal, and (3) abuse liability of NPs.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Current established users of nicotine pouches (have used nicotine pouches in the past 30 days \& currently use nicotine pouches every day or someday) * Positive cotinine test via saliva test strip * Those who are unmotivated to quit nicotine use * Read and speak English. * Poly-users of nicotine pouches, e-cigarettes (e.g., vape ≥20 days/month), and tobacco (e.g., ≥4 cigarettes/day for ≥2 years) will be eligible for participation Exclusion Criteria * Planning to cut down or quit using nicotine in the next 30 days * Currently pregnant or breastfeeding * History of stroke, seizures, high blood pressure, heart disease/problems, or cardiovascular disease contraindications for nicotine.
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What it tests

  • Nicotine pouch: Low dose
  • Nicotine pouch: High dose
  • Low pH
  • High pH
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Where

1 site
Rollins School of Public Health
Atlanta, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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