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Comparison of Two SpO2 Targets With Two Different Oximeters - Impact on FiO2 During Nasal High Flow Oxygen Therapy

RecruitingNAAges 18 Years - anyAllLaval University
NCT07168213 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Several factors can influence oxygenation monitoring and respiratory support through oxygen therapy: the type of oximeter used, skin pigmentation, and the oxygenation target. It is essential to have an accurate measurement of SpO2 in order to optimize the flow of oxygen or FiO2 administered to patients. The question arises as to the impact of these confounding factors on the FiO2 set during high-flow nasal oxygen therapy. The aim of the study is to evaluate the impact of the oxygenation target and the oximeter used on FiO2 in patients receiving high-flow nasal oxygen therapy.

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📋 Eligibility rules (as published)
Inclusion Criteria: * ≥ 18 years of age * Admiitted in intensive care unit * Presence of an arterial catheter * Ongoing on high flow nasal oxygen therapy with SpO2 between 88 and 100% with a FiO2 between 40 and 80% with the usual oximeter . Exclusion Criteria: * No SpO2 signal with oximeter in use * False nails or nail polish * Methemoglobinemia \>0.015 on last available arterial gas * Patient in isolation (multi-resistant bacteria, C-Difficile, SARS-CoV-2 ...) * Expected to use another respiratory support within two hour of inclusion (NIV or mechanical ventilation)
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What it tests

  • Manual FiO2 titration with Philips oximeter (SpO2 target 90%)
  • Manual FiO2 titration with Nonin oximeter (SpO2 target 90%)
  • Manual FiO2 titration with Philips oximeter (SpO2 target 94%)
  • Manual FiO2 titration with Nonin oximeter (SpO2 target 94%)
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Where

1 site
Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval
Québec, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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