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Observation Study on Reducing the Risk of Liver Cancer Associated With Hepatitis B (Zhiyuan) Project.

Recruitingn/aAges 18 Years - anyAllThe First Affiliated Hospital of Zhengzhou Univer…
NCT07169656 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study is a multicenter, prospective, observational real-world study designed to investigate and analyze the current treatment patterns of chronic hepatitis B (CHB) across 200 hospitals in China. By comparing patient outcomes under different therapeutic regimens, it aims to provide high-quality evidence-based medical data to optimize CHB treatment strategies and follow-up protocols, ultimately contributing to the advancement of a functional cure for chronic hepatitis B.

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📋 Eligibility rules (as published)
Inclusion Criteria: * 1.Chronic HBV infection (HBsAg-positive for ≥6 months); 2.Age ≥18 years; 3.Patients who, based on real-world clinical practice needs, are planned or currently receiving treatment with:Entecavir (ETV),Tenofovir disoproxil fumarate (TDF),Tenofovir alafenamide fumarate (TAF),Tenofovir amibufenamide (TMF) OR Pegylated interferon α-2b-naïve patients OR Patients re-initiating pegylated interferon α-2b therapy; 4.Written informed consent obtained from the patient. Exclusion Criteria: * 1.Severe hepatic dysfunction or decompensated cirrhosis; 2.Concurrent participation in other clinical trials; 3.Hepatocellular carcinoma (HCC).
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What it tests

  • ETV,TDF,TAF,TMF
  • Peginterferon α-2b injection
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Where

162 sites
Huaxian People's Hospital
Anyang, China
Linzhou City People's Hospital
Anyang, China
Neihuang County People's Hospital
Anyang, China
Tangyin County People's Hospital
Anyang, China
The Fifth People's Hospital of Anyang
Anyang, China
The First Affiliated Hospital of Xinxiang Medical University (Hua County Branch)
Anyang, China
Guangzhou First People's Hospital
Guangzhou, China
The First Affiliated Hospital of Jinan University (Guangzhou Overseas Chinese Hospital)
Guangzhou, China

…and 154 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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