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โ† Trials
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Effect of Protocolized Magnesium Replacement on Mortality and Atrial Fibrillation in Critically Ill Patients

RecruitingPhase 4Ages 16 Years - anyAllScarborough General Hospital
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In plain words

What the trial is, and whether it could suit you

In patients with critical illness, such as severe infections, heart attacks, or respiratory failure, most intensive care units (ICUs) measure magnesium levels and give supplemental doses of magnesium when levels are below certain targets. However, the best targets are unknown. The goal of this clinical trial is to study protocols for magnesium supplementation in people with critical illness, comparing a protocol with higher target level to a protocol with a lower target level. The main question this study aims to answer is whether magnesium supplementation protocols targeting a higher or lower level lead to better 30-day survival and less atrial fibrillation. Participants will not have to do any specific tasks, undergo any additional tests, or complete any surveys.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age 16 years or older * Admission orders written to a medical-surgical intensive care unit at a participating site * Magnesium replacement protocol ordered Exclusion Criteria: * Prior enrollment in or withdrawal from MAGNOLIA trial * Sustained ventricular tachycardia * Pre-eclampsia * Myasthenia gravis
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What it tests

  • Magnesium sulfate administration
  • Magnesium oxide
  • Magnesium glucoheptonate
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Where

6 sites
Lakeridge Health Ajax-Pickering
Ajax, Canada
Lakeridge Health Bowmanville
Bowmanville, Canada
Lakeridge Health Oshawa
Oshawa, Canada
Scarborough Centenary Hospital
Toronto, Canada
Scarborough General Hospital
Toronto, Canada
Scarborough Birchmount Hospital
Toronto, Canada
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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