🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Contrast and Anesthetic Level With Lumbar Erector Spinae Plan (ESP) Block

RecruitingNAAges 21 Years - 75 YearsAllUniversity Hospitals Cleveland Medical Center
NCT07174440 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

As per usual care for spine surgery, participants will have their back cleaned with alcohol and a needle will be placed using ultrasound for the ESP block. Through the needle, a small catheter will be placed in the participants back and the needle removed. Approximately one hour prior to the start of surgery, a numbing medication (ropivacaine, similar to Novocaine) in combination with dexmedetomidine (a pain medicine that is used in nerve block and that is not a narcotic) and contrast dye (iohexol) will be injected through the catheter. Participants will then go through the QST procedure (test of buzzing sensation and temperature sensation through pads applied to their skin) to assess the numb areas and then head to the operating room. In the operating room, the catheter will be removed after the surgeon obtains baseline CT scan images of the spine. Once surgery is completed, investigato

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Age range: Adult patients 21-75 years of age * ASA status: I-III * Planned lumbar spine fusion involving no more than three levels * Ability to ambulate prior to surgery Exclusion Criteria: * Previous lumbar spine surgery * Metastatic cancer with involvement of the lumbar spine * eGFR \< 60 mL/min/1.73m2 * Active liver disease (hepatitis or cirrhosis) * Confirmed allergy to ropivacaine, dexmedetomidine or iohexol * Cognitive impairment resulting in inability to rate pain scores * Patients receiving 30 mg or more of morphine equivalent daily dosing preoperatively * Pregnancy
💊

What it tests

  • Ropivacaine (Epidural analgesia)
  • Dexmedetomidine
  • Iohexol
  • QST Procedure
📍

Where

1 site
University Hospitals Cleveland Medical Center
Cleveland, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy