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Scrambler Therapy in Chronic Pancreatitis

RecruitingNAAges 18 Years - anyAllJohns Hopkins University
NCT07174609 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The investigators will enroll adults with chronic pancreatitis who have persistent abdominal pain not relieved by standard treatments. This study will test the feasibility and effectiveness of Scrambler Therapy, a non-invasive FDA-cleared device that delivers "non-pain" electrical signals through the skin to retrain the brain's pain perception. Participants will undergo 5-10 treatment sessions and be followed for 3 months with standardized pain scores and quality-of-life assessments. The goal is to generate pilot data to support larger studies of Scrambler Therapy as a novel option for pancreatic pain.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged 18 years and older * Diagnosis of chronic pancreatitis with refractory abdominal pain * Able to provide written informed consent in English * Sufficient English language ability to complete study questionnaires * Reliable and regular access to a phone for follow-up Exclusion Criteria: * Unable or unwilling to provide written consent * History or presence of a significant medical or psychiatric condition that would interfere with study participation * Pregnant or lactating women * Coronary stents or implanted metallic/electrical devices (pacemaker, defibrillator, aneurysm clips) * History of epilepsy, traumatic brain injury, or myocardial infarction within the past 6 months * Skin conditions preventing electrode placement (e.g., open wounds) * Any condition that, in the investigator's opinion, places the participant at increased risk or prevents full compliance with study procedures
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What it tests

  • Scrambler Therapy
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Where

1 site
Johns Hopkins Green Spring Station
Baltimore, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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