AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Innovative Approaches to Enhance Balance and Neuroplasticity in Multiple Sclerosis

RecruitingNAAges 18 Years - 65 YearsAllUniversity Health Network, Toronto
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

This study will evaluate the effects of combining balance training with electrical stimulation techniques in individuals with Multiple Sclerosis (MS). MS commonly impairs leg strength, coordination, and balance, increasing the risk of falls and reducing independence. The interventions include:Balance training only, Balance training with Functional Electrical Stimulation (FES), and Balance training with FES and Transcutaneous Spinal Cord Stimulation (TSCS). FES delivers small electrical pulses to leg muscles, while TSCS delivers electrical signals through the skin to stimulate the spinal cord and enhance motor control. The study will enroll up to 24 participants over a 3-year period. This trial is funded by MS Canada. Participants will be randomly assigned to one of three groups: (1) balance training only, (2) balance training with FES, or (3) balance training with FES and TSCS. All part

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Participants will be eligible if they meet the following conditions: * Confirmed diagnosis of Multiple Sclerosis (MS) according to the revised McDonald criteria * Age โ‰ค 65 years * Ability to walk at least 100 meters, with or without an assistive device, and without requiring rest * Self-reported perception of impaired balance during standing or walking in daily activities Exclusion Criteria: * Participants will be excluded if they present with any of the following: * Uncorrected visual problems * Cognitive impairment affecting comprehension of instructions or completion of self-administered outcome measures * Ongoing MS exacerbation or paroxysmal vertigo * Concurrent neurological or orthopedic conditions affecting balance * Recent participation in rehabilitation therapies (physical therapy, occupational therapy, or vestibular therapy) within one month prior to recruitment * Planned or recent injection of botulinum toxin to the legs during the intervention period * Peripheral nerve damage affecting the legs * Contraindications to electrical stimulation, including:implanted electronic device, active cancer or radiation treatment within the past 6 months, uncontrolled epilepsy, skin rash or open wound at electrode site, pregnancy, active deep vein thrombosis
๐Ÿ’Š

What it tests

  • Balance training with FES
  • Balance training wiith combined neuromodulation (TSCS+FES)
  • Balance training only
๐Ÿ“

Where

1 site
Toronto Rehabilitation Institute-Lyndhurst Center
Toronto, Canada
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy