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Low Serum Creatinine as a Predictor of Prolonged Mechanical Ventilation and Weaning Failure

RecruitingNAAges 18 Years - anyAllUniversity Hospital Ostrava
NCT07177183 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The main objective of the study is to determine whether a subnormal serum creatinine value upon admission to the Post-ICU Care Unit predicts the need for prolonged ventilatory support. A parallel objective of the study is to determine whether exogenous in-take of the dietary supplement creatine in patients with subnormal serum creatinine value is associated with a shortened duration of ventilatory support and improved patients outcome.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients \<18 years of age * Patients admitted to post-ICU care units at Chronicare Group a.s. in the Czech Republic within 12 months Exclusion Criteria: * Patients who are unlikely to be weaned from ventilatory support. * Patients in palliative care or with a survival probability of \<3 months * Patients with advanced malignancy * Patients with a history of chronic kidney disease * Patients with a history of chronic liver disease * Patients with supranormal serum creatinine on admission to the post-ICU care unit * Patients who refused to sign the Informed Consent with participation in the study.
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What it tests

  • Dietary supplement creatine
  • Dietary supplement - placebo
  • No intervention
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Where

2 sites
Chronicare Mund s.r.o.
Brno, Czechia
Chronicare s.r.o.
Milovice, Czechia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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