🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Remote Ischaemic Conditioning for Post-surgical Complications in Hip Fracture (RIC-FRACTURE)

RecruitingNAAges 18 Years - anyAllSheffield Teaching Hospitals NHS Foundation Trust
NCT07178041 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Background Hip fracture affects 70,000 people in the United Kingdom (UK) and costs an estimated £1.1 billion per year to the National Health Service (NHS). Key clinical indicators, such as early surgical repair, have been shown to improve patient outcomes, however morbidity and mortality remain extremely high, reflecting the urgent need for novel therapies to enhance outcomes. Common complications include infection, cardiovascular events, falls and venous thromboembolism. Remote Ischaemic Conditioning (RIC) is a treatment whereby a blood pressure cuff is inflated around an arm or leg to above systolic pressures to occlude blood flow to the limb for short periods of time, that do not result in harm, but trigger innate mechanisms that reduce inflammation, improve organ blood flow and improve bone healing. These may be beneficial effects after hip fracture. Methods This is a single centre,

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Adults (aged \> 18 years) * Participant has had a hip fracture identified on X-ray or computed tomography (CT) scan. * Qualifying hip fracture has not occurred more than 7 days prior to enrollment. * Able to give written informed consent. * In the opinion of the treating physician would be able to conform to the study protocol and procedures. Exclusion Criteria: * History or presence of significant peripheral vascular disease in the limb conditioned. * History or presence of complex neuropathic pains or peripheral neuropathy in the limb conditioned. * Presence of lymphoedema in the limb conditioned. * Presence of skin ulceration to the limb conditioned. * Uncontrolled arrhythmia, hypertension, diabetes or angina. * Third degree heart block or progressive heart failure. * Acute aortic dissection, myocarditis, or pericarditis. * Acute deep vein thrombosis, pulmonary embolism. * Suspected or known dissecting aneurysm. * Stroke or TIA myocardial infarction in the last 4 weeks.
💊

What it tests

  • Remote Ischaemic Conditioning
📍

Where

1 site
Sheffield Teaching Hospitals NHS Foundation Trust
Sheffield, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy