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Using a Hypotension Prediction Index to Prevent Low Blood Pressure During Dialysis in ICU Patients

RecruitingNAAges 18 Years - anyAllChulalongkorn University
NCT07179705 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This single-center, crossover randomized controlled trial (HyPIR-ICU) investigates whether a Hypotension Prediction Index (HPI)-guided management strategy can reduce intradialytic hypotension (IDH) during prolonged intermittent renal replacement therapy (PIRRT) in critically ill patients. All participants must have an indwelling arterial catheter for continuous hemodynamic monitoring.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults \>18 years old * Diagnosed with acute kidney injury (AKI) or end-stage kidney disease (ESKD) * Admitted to medical ICU * Scheduled for PIRRT * Have an indwelling arterial catheter Exclusion Criteria: * Severe right heart dysfunction, significant valvular disease, arrhythmias, mechanical circulatory support, absence of arterial access, no UF prescription, palliative care, or expected ICU stay \<72 hours.
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What it tests

  • Hypotensive prediction index
  • Standard of care monitoring
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Where

1 site
Division of Nephrology, Faculty of Medicine, Chulalongkorn University
Bangkok, Thailand
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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