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The Effectiveness of Intermittent Fasting, Caloric Restriction and Physical Activity On Metabolic Syndrome

RecruitingNAAges 18 Years - 80 YearsAllUniversiti Putra Malaysia
NCT07181655 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Metabolic syndrome (MetS) is a global health issue defined by a cluster of risk factors-abdominal obesity, elevated blood pressure, high fasting blood sugar, high triglycerides, and low HDL cholesterol-that together significantly increase the risk of cardiovascular disease, type 2 diabetes, and overall mortality. Globally, about 20-25% of adults are affected, but prevalence varies by region and population; in Saudi Arabia, studies report rates ranging from 28.3% to 56.4%, with higher rates observed in northern and central regions and among men. Major contributors to MetS in Saudi Arabia include obesity, sedentary lifestyle, smoking, and poor dietary habits, such as low fruit consumption. Effective management strategies focus on weight loss through caloric restriction, intermittent fasting, and increased physical activity, all of which have demonstrated improvements in metabolic markers l

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📋 Eligibility rules (as published)
Inclusion Criteria: * The inclusion criteria will be adult aged 18 years and above who have three or more of the following five risk factors (Kunduraci \& Ozbek, 2020): * Abdominal obesity. * Elevated triglycerides. * Low HDL cholesterol. * Elevated blood pressure. * Elevated fasting blood glucose. Exclusion Criteria: * Being pregnant, lactating women. * Diagnosis of cardiac failure or/and severe renal or liver diseases, cancer. * Having had bariatric surgery. * Physical or mental disability. * Neurological or cognitive impairment. * Participant with severely impaired vision, hearing, or speech. * Following a special diet or having changed their dietary pattern within the previous 12 weeks of the study's start date. * Use of insulin or sulphonamide derivative oral antidiabetic drugs. * Conditions that will seriously affect weight management such as having had bariatric surgery.
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What it tests

  • Modified Intermittent Fasting
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Where

1 site
Associate Professor Dr. Hazizi Abu Saad
Serdang, Malaysia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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