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MSC Exosome Therapy for Post-Preeclampsia Endothelial Dysfunction

RecruitingPhase 1, Phase 2Ages 18 Years - 50 YearsFemaleUniversitas Padjadjaran
NCT07183384 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

\--- Why Is This Study Being Done? Women who have preeclampsia during pregnancy face a much higher risk of heart disease later in life. Preeclampsia is a serious pregnancy condition that causes high blood pressure and damages blood vessels. Even after the baby is born, the blood vessels do not fully heal on their own, which can lead to heart problems/cardiovascular years later. This study tests whether a new treatment called exosomes can help repair damaged blood vessels in women who had preeclampsia. Exosomes are tiny particles that come from stem cells and contain healing substances that may help blood vessels work better. \--- What Will Happen in This Study? This study will include 80 women who recently gave birth and had preeclampsia during their pregnancy. Half of the women will receive the exosome treatment through an IV, and half will receive a placebo (a substance with no a

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📋 Eligibility rules (as published)
Inclusion Criteria: * Postpartum * Confirmed diagnosis of preeclampsia in the last pregnancy * Postpartum period of first week and second week * Able to provide informed consent Exclusion Criteria: * History of chronic hypertension prior to pregnancy * Major cardiovascular disease history * Active systemic infection * Endothelial Injury history * Active smoking status including vape, alcohol, drug addiction.
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What it tests

  • Mesenchymal Stem Cell-Derived Exosomes
  • Placebo (Sterile Saline Solution)
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Where

1 site
Dr. Hasan Sadikin Central General Hospital
Bandung, Indonesia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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