Impact of Infusion Line Change Frequency on Infectious Complications Related to Central Venous Catheters in the ICU - A Randomized Controlled Trial

Inclusion criteria * Adult patient * Any ICU patient with a central venous catheter (inserted by venipuncture) in place for less than 72 hours and with an expected dwell time of at least 7 days * Patient affiliated with or covered by a social security system * Patient who has given verbal consent or written consent from a third party or in the event that the patient is unable to give consent. Exclusion Criteria * Patient with a documented bloodstream infection at the time of inclusion * Patient whose central venous catheter has been in place for more than 72 hours * Patient with suspected catheter-related infection * Patient whose study catheter was inserted using a guidewire exchange * Patient previously enrolled in the study during the same ICU stay * Patient whose condition, according to the clinician, does not allow safe placement of a central venous catheter, such as: * Allergy to catheter material * Confirmed deep vein thrombosis at the time of insertion * Inflammatory skin disorder at the insertion site * Patient admitted for extensive burns * Inadequate understanding of the French language * Pregnant, breastfeeding, or postpartum woman * Person deprived of liberty by judicial or administrative decision * Person receiving involuntary psychiatric care * Person under legal guardianship or other legal protection measure