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Investigating the Impact of Electrical Stimulation on Facial Pain, Jaw Movement and Oral Health in People With Motor Neuron Disease.

RecruitingNAAges 18 Years - anyAllNova Southeastern University
NCT07187388 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to evaluate the impact of non-invasive electrical stimulation, when placed on the facial muscles can reduce facial pain and improve jaw mobility, and chewing in individuals with Amyotrophic Lateral Sclerosis (ALS) and Primary Lateral Sclerosis (PLS). The secondary goal is to evaluate the impact of non-invasive electrical stimulation on patient reported difficulty performing oral hygiene tasks in individuals with ALS and PLS. Participants will attend one in-person clinic visit and participate in one telephone interview 24 hours after the treatment. The clinic visit will include pre-intervention assessments, a single 30-minute treatment of electrical stimulation followed by post-intervention assessments. The assessments will include a self-rating of jaw and facial pain, a range of motion test where participants will be asked to open their jaw as wide and

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of possible, probable, or definite ALS (El-Escorial Revisited) OR diagnosis of definite PLS by the treating neurologist and based on the consensus diagnostic criteria for PLS * Subjective report of jaw pain, indicated by a NRS score of \> or = 3/10. Exclusion Criteria: * history of head or neck cancer * history of CVA * history of past facial surgery with hardware placement * history of pacemaker * diagnosis of significant cognitive impairment by the treating physician * history of seizures or diagnosis of epilepsy * open wound at the area of electrode placement * complete loss of sensation at the area of electrode placement
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What it tests

  • Transcutaneous Electrical Nerve Stimulation to reduce facial pain and improve jaw range of motion in ALS and PLS
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Where

1 site
Nova Southeastern University, David and Cathy Husman Neuroscience Institute
Davie, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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