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Youth Suicide Risk Factors, Reduction of Suicide Risk Factor in Youth People

RecruitingNAAges 18 Years - 25 YearsAllFondazione Policlinico Universitario Agostino Gem…
NCT07188506 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The YOU-SURF project is at the forefront of youth suicide prevention, with the goal of integrating multimodal clinical and neurobiological data to comprehensively identify risk factors and the most effective intervention strategies. Suicide is one of the leading causes of death among young people, with particularly alarming incidence rates during adolescence and early adulthood. Suicidal risk is a complex phenomenon, determined by a multiplicity of clinical, environmental, and biological factors. Emerging evidence suggests that information derived from neuroimaging, genetics, and the microbiome may also play a significant role. However, studies conducted to date have not yet adopted a truly multimodal approach that jointly integrates these dimensions in the identification of risk factors for suicide in youth. The YOU-SURF project aims to fill this critical gap. YOU-SURF will also pionee

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of mood disorder (major depressive episode, major depressive disorder, or bipolar disorder) according to DSM-5; * Age between 18 and 25 years; * Eligibility for magnetic resonance imaging; * Proficiency in the Italian language. Exclusion Criteria: * Comorbidity with severe neurological or medical conditions; * Diagnosis of cognitive impairment; * Inability to provide informed consent. For the control group: Inclusion Criteria: the same as the experimental group. Exclusion Criteria: * subjects with DSM-5 disorders * subjects with a family history of psychiatric disorders will be excluded.
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What it tests

  • Clinical and blood parameters
  • Illumina Infinium Global Screening Array 4.0 (GSA 4.0)
  • dTMS treatment
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Where

1 site
Fondazione Policlinico Universitario A. Gemelli IRCCS - UOC Psichiatria Clinica e d'Urgenza
Roma, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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