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โ† Trials
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Culturally Adapted Cognitive Behavior Therapy for Individuals At Risk of First Episode Psychosis

RecruitingNAAges 16 Years - 35 YearsAllPakistan Institute of Living and Learning
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In plain words

What the trial is, and whether it could suit you

Young people constitute nearly half of Pakistan's population and are highly vulnerable to risk factors for mental illness, including poverty, inequality, abuse, and violence. Estimates suggest that 19-34% of children and adolescents experience emotional or behavioural disorders, though this is likely underestimated. In recent years, research has focused on those at imminent risk of developing serious conditions such as first episode psychosis. The concept of an At-Risk Mental State (ARMS) has highlighted the urgent need for interventions that address current symptoms, improve functioning, and reduce transition to psychosis. Up to 80% of young people with ARMS have another diagnosable condition, and almost half show poor psychosocial outcomes even six years after initial help-seeking. Evidence demonstrates that early identification and treatment can delay or prevent psychosis, including

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Male or female help-seeking individual aged 16-35 years; * Score 6 or above on PQ-16 * Meet the at risk of FEP criteria using CAARMS Operationalized Intake Criteria based on three groups (vulnerability, attenuated psychosis or brief limited intermittent psychotic symptoms group); * Assessed as competent to provide informed consent. * Give written informed consent. Exclusion Criteria: * Temporary resident unlikely to be available for follow up. * Unable to engage, participate or respond to research questionnaires. * a history of psychotic illness (treated or untreated). * previous treatment with an antipsychotic or mood-stabilising agent. * active substance abuse (except nicotine or caffeine) or dependence within the last three months, according to DSM-V criteria.
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What it tests

  • Cognitive Behavior Therapy for those at risk of first episode psychosis
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Where

2 sites
Commuity/Schools/Colleges
Karachi, Pakistan
Karwan e Hayat
Karachi, Pakistan
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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