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Prilocaine for Sphenopalatine Ganglion Block in Endoscopic Hypophysectomy

RecruitingNAAges 21 Years - 45 YearsAllKasr El Aini Hospital
NCT07188987 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Patients undergoing endoscopic surgeries for pituitary adenoma excision suffer from wide swings in blood pressure that might increase bleeding and interfere with the surgical field. Local anethetic infiltration and regional nerve blocks have been used to provide better analgesia, control blood pressure and improve surgical field. Limited studies evaluated shenopalatine ganglion block in pituitary adenoma excision with promising outcomes. The proposed study will compare the efficacy of two local anesthetics, prilocaine and lidocaine, for spenopalatine ganglion block in patients undergoing endoscopic pituitary adenoma excision. Evaluating the control of the intraoperative blood pressure and analgesic sparing are the main objectives of the proposed study.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with pituitary adenoma undergoing endoscopic hypophysectomy. * ASA physical status I and II. * Age above 21, below 45 years. * Male or female Exclusion Criteria: * Any patient below 21 years or above 45 years. * Patients suffering from any of the following conditions: * Disturbed conscious level. * Coagulation abnormalities. * Poorly controlled blood pressure and/or heart rate. * Increased intracranial tension. * Liver and kidney disorders. * Patients on anticoagulants and/or NSAIDS (non-steroidal anti- inflammatory drugs * Patients addicted to drugs and/or alcohol. * Patients with disturbed conscious level at the end of the surgery, GCS \>14
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What it tests

  • Sphenopalatine Ganglion Block using 2% lidocaine
  • Sphenopalatine Ganglion Block
  • Sphenopalatine Ganglion Block
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Where

1 site
Kasr El Ainy
Cairo, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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