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To Compare Post-Extraction Use of a Novel Ethylenediaminetetraacetic Acid (EDTA) Post-operative Mouth Rinse and Daily Use EDTA Mouth Rinse and Standard 0.12% Chlorhexidine (CHX) Post-operative Mouth Rinse and Daily Use Essential Oil (EO) Mouth Rinse.

RecruitingNAAges 18 Years - 85 YearsAllUniversity of Alabama at Birmingham
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In plain words

What the trial is, and whether it could suit you

This study will compare commercially available, commonly used mouth rinses (0.12% chlorhexidine (CHX) vs. Ethylenediaminetetraacetic acid (EDTA)) for immediate post-operative and daily antiseptic use after tooth extraction and ridge preservation grafting followed by daily use of commercially available an essential oil (EO) mouthrinse and EDTA mouthrinse.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Able to read and provide informed consent in English * At least 18 years old * Established and registered patient of the UAB School of Dentistry * Patients presenting with one single rooted tooth determined to need extraction and simultaneous ridge preservation bone grafting for future dental implant placement. * Presence of periodontally healthy, non-carious neighboring teeth and/or healthy restored dental implants on either side of the tooth planned for extraction. * No anticipated need for surgical and/or endodontic care at teeth adjacent to the proposed surgical site during the study period. Exclusion Criteria: * Non-English speaking * Age less than 18 years old or older than 85 years old * Smokers/nicotine users (\>10 cigarettes or equivalent/day) * Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing * Multiple adjacent teeth require extraction and grafting * Absence of adjacent teeth/implants on either side of the tooth to be extracted. * Documented or suspected allergy or sensitivity to any study product
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What it tests

  • 0.12% CHX and Essential Oil mouthrinse
  • 2.6% EDTA and 0.2% EDTA mouth rinse
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Where

1 site
University of Alabama at Birmingham
Birmingham, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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