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Efficacy of Photodynamic Therapy in the Non-Surgical Treatment of Peri-Implantitis

RecruitingNAAges 18 Years - anyAllEgas Moniz - Cooperativa de Ensino Superior, CRL
NCT07191522 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Peri-implantitis is a growing public health problem that can lead to several complications and sequelae, with a serious impact on the health and quality of life of patients and a high cost for healthcare systems. Bacterial plaque that accumulates around dental implants leads to peri-implant tissue inflammation that ultimately can result in the loss of the implant, significant bone destruction and infection that can reach other regions. Successful implant decontamination is necessary to preserve the implant and several strategies have been suggested for this purpose, however, there is still no fully effective treatment modality and failures and recurrence are relatively frequent. To better understand this problem and develop more effective treatment strategies, investigators will first conduct an epidemiological study to understand the factors associated with the development of this pat

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📋 Eligibility rules (as published)
Inclusion Criteria: * patients over 18 years of age; * patients with one or more implants diagnosed with peri-implantitis rehabilitated for at least one year; * PI and GI \< 25%. Exclusion Criteria: * smoking patients; * patients with uncontrolled periodontitis; * systemic diseases that influence the study (diabetes); * inadequate prosthetic rehabilitation that cannot be modified or that prevents access for physical decontamination; * implants rehabilitated with cemented crowns; * pregnant and lactating women; * previous surgical intervention at the same site; * therapy with non-steroidal anti-inflammatory drugs (NSAIDs), antibiotics or immunosuppressants in the last 3 months; * patients previously undergoing chemotherapy or radiotherapy; * PI and IG \> 25%; * uncooperative patients.
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What it tests

  • Mechanical debridment with titanium curettes and ultrasounds
  • Mechanical debridment with titanium curettes and ultrasounds + aPDT (antimicrobial photodynamic therapy)
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Where

1 site
Egas Moniz School of Health and Science
Almada, Portugal
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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