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โ† Trials
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Assessing Uterine Cancer Risk in Lynch Syndrome Carriers Using Vaginal Self-sampling and a Health Questionnaire

RecruitingNAAges 30 Years - anyFemaleUniversity of British Columbia
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In plain words

What the trial is, and whether it could suit you

The goal of this study is to find out if self-collected vaginal swabs can be used to detect early signs of uterine cancer or related conditions in people with Lynch syndrome (LS) who still have their uterus. The study also tests if people with LS are willing and able to collect these samples themselves and whether they find the process acceptable. The main questions this study asks are: * Will people with LS take part in self-collection of vaginal samples, and do they find it acceptable? * Can vaginal DNA mutations predict cancer risk or match results from other genetic or biopsy testing? * Can a cancer risk model used in the general population also help identify risk in people with LS? Participants will: * Answer a health questionnaire about lifestyle and symptoms * Collect their own vaginal swabs and measure their vaginal pH at home using a self-collection kit * Complete short surv

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Diagnosed with Lynch syndrome (confirmed by genetic testing). * Have an intact uterus. * Age 30 years or older. Exclusion Criteria: * History of endometrial cancer or endometrial hyperplasia. * History of pelvic radiation or endometrial ablation. * Pregnant at the time of study enrolment or during the study.
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What it tests

  • Vaginal DNA swab, microbiome swab and pH test
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Where

1 site
VGH Research Pavilion
Vancouver, Canada
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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