🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

The Efficiency of 810 nm Diode Laser on Periapical Healing After Root Canal Retreatment

RecruitingNAAges 20 Years - 45 YearsAllAl-Azhar University
NCT07194837 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The main cause of endodontic disorders is microbial infection. From the infected root canal, microorganisms can penetrate into the deeper layers of root dentine and propagate a periapical tissue through the apical foramen and lateral canals. Eliminating microorgnims is the primary objective of endodontics in order to create an environment as free of bacteria as possible. This will favor the environment for healing without the need of periapical surgery in some resistant cases. Disinfection in root canal retreatment (RCR) is much more difficult because persistent microorganisms have settled in the root canal. The resistant periapical lesions result from resistant bacteria to antimicrobial agents. They can survive for years around the filled root canals. Sodium hypochlorite (NaOCl) is the most widely used irrigant in root canal therapy due to its strong antibacterial effect and its abilit

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Patients have single rooted teeth with root canal form type I. * Have previous endodontic therapy with failure. * Have periapical radiolucency (PAI score of 3 or 4). * Patients who provide written informed consent. Exclusion Criteria: * Patients who had received antibiotic therapy within the past month. * Pregnancy and lactation. * Systemic disease. * Physical or mental disability. * Non restorable teeth. * Any signs of resorption, immature roots, fracture, perforation. * Bone metabolism disease and/or patients using drugs that affect bone metabolism (such as steroids and bisphosphonates)
💊

What it tests

  • diode laser
  • Calcium Hydroxide (Ca(OH)2)
📍

Where

1 site
from the outpatient clinic of Endodontic Department, Faculty of Dental Medicine for Girls, Al-Azhar University
Cairo, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy