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Effects of Fecal Microbiota Transplantation

Recruitingn/aAges 18 Years - 50 YearsAllUniversity Hospital, Rouen
NCT07196189 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The intestinal microbiota plays an essential role in digestion and, through the gut-brain axis, in the regulation of weight gain and eating behavior. The balaEating disorders (EDs) are serious pathologies affecting adolescence and young adults, likely to become chronic, with long-term morbidity and mortality impacts. These pathologies represent a very important public health issue. EDs are defined by the DSM-V classification criteria and include different forms: anorexia nervosa, bulimia nervosa, hyperphagia, and atypical or unspecified forms. The global prevalence of these diseases reaches 8.4% in women and 2.2% in men. These eating disorders lead to numerous psychiatric and somatic complications and have a significant impact on the quality of life and mortality of patients (particularly in anorexic patients). The molecular mechanisms underlying eating disorders are still poorly underst

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📋 Eligibility rules (as published)
Inclusion Criteria: Patients with ED * Women. * Aged 18 to 50. * First consultation in the Nutrition Department of Rouen University Hospital for ED. * Positive SCOFF with diagnosis of anorexia nervosa, bulimia nervosa, or binge eating disorder. * Affiliation with a social security plan. * Patient who has read and understood the information letter and does not object to participating in the study. Healthy Volunteers * Women. * Aged 18 to 50. * Body mass index between 18.5 and 24.9 kg/m². * SCOFF test: no positive response. * No history of ED or active ED (DSM V criteria negative). * Affiliation with a social security plan. * Individual who has read and understood the information letter and does not object to participating in the study. Exclusion Criteria: Patients with ED * Men. * Aged under 18 and over 50. * Negative SCOFF. * Patients who have received antibiotic treatment in the last 3 months. * Patients with a history of IBD or surgical procedures on the digestive tract. * Patient refuses to participate in the study. * Persons deprived of liberty by judicial or administrative order. * Pregnant or breastfeeding women. * Protected persons (guardianship or curatorship). Healthy volunteers * Men. * Aged under 18 and over 50. * SCOFF test with at least one positive response. * History or active ED (DSM V criteria). * Persons who have received antibiotic treatment in the last 3 months. * Person with a history of IBD or surgical procedures on the digestive tract. * Body mass index less than 18.5 or greater than 24.9 kg/m2. * Pregnant or breastfeeding women. * Protected persons (guardianship or curatorship).
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What it tests

  • Patients
  • healthy volunteer
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Where

1 site
University Rouen Hospital
Rouen, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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