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OCT-Guided Stent Optimization for Short-Duration Dual Antiplatelet Therapy in Stable Angina

RecruitingNAAges 19 Years - anyAllKorea University Guro Hospital
NCT07198529 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to evaluate whether the use of optical coherence tomography (OCT), an advanced intravascular imaging tool, can improve stent implantation results and make it possible to shorten the duration of dual antiplatelet therapy (DAPT) in patients with stable angina who undergo percutaneous coronary intervention (PCI). PCI with drug-eluting stents is a standard treatment for patients with stable angina, and these patients are usually prescribed DAPT for 6 to 12 months to prevent stent thrombosis and other complications. However, extended use of DAPT increases the risk of bleeding, which can lead to significant medical problems, especially in patients with high bleeding risk. OCT provides detailed, high-resolution images of the coronary arteries and the implanted stents, allowing physicians to optimize stent expansion and positioning. By ensuring that the stent is well-placed and

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients who undergo PCI using a cobalt-chromium everolimus-eluting stent (CoCr-EES) * Diagnosis of stable angina * Ability and willingness to provide written informed consent approved by the Institutional Review Board (IRB), and to comply with the study protocol and clinical follow-up schedule * Age ≥ 19 years Exclusion Criteria: * Patients diagnosed with acute coronary syndrome (ACS), including unstable angina or acute myocardial infarction * Contraindications to antiplatelet therapy or OCT imaging * Presence of lesions with severe stenosis, heavy calcification, or marked vessel tortuosity that prevent passage of a guidewire or catheter * Patients with previously implanted coronary stents in the target lesion
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What it tests

  • Short DAPT
  • Standard DAPT
  • Extended DAPT
  • OCT-guided PCI
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Where

1 site
Cardiovascular Center, Department of Internal Medicine, Korea University Guro Hospital
Seoul, South Korea
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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