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Randomized, Double-blind Crossover Trial Comparing Low-GI Functional vs. Standard Wholegrain Carbohydrates on Glycolipid Metabolism and Vascular Stress Markers in Adults With Suboptimal Triglyceridemia

RecruitingNAAges 18 Years - anyAllUniversity of Bologna
NCT07198789 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Low-glycemic index (GI) carbohydrates help prevent type 2 diabetes and cardiovascular disease by reducing postprandial glucose, insulin spikes, inflammation, and triglyceride synthesis. They improve weight, lipid profiles, and vascular health. Our study will compare functional low-GI vs. standard wholegrain carbs in a Mediterranean diet to assess their effect on the Triglycerides-Glucose Index, a marker of metabolic and cardiovascular risk, in subjects with suboptimal triglyceride levels.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Male or female aged ≥ 18 years * TG\>150 mg/dL * Subjects who have the capability to communicate and to comply with the study's requirements. * Subjects agree to participate in the study and having dated and signed the informed consent form. Exclusion Criteria: * Gluten hypersensitivity/Coeliac disease diagnosis * BMI\>30 kg/m2 * Any preventive treatments (i.e. lipid-lowering drugs, antihypertensives) not stabilized in type and dose for at least 3 months * Any medical or surgical condition that would limit the patient adhesion to the study protocol.
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What it tests

  • Altograno® Bakery Foods
  • Standard Whole-Grain Bakery Foods
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Where

1 site
Cardiovascular Internal Medicine Unit, IRCCS University Hospital of Bologna, Bologna, Italy
Bologna, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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