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Gingival Phenotype and Dental Crowding in Pediatric Patients

Recruitingn/aAges 5 Years - 16 YearsAllFondazione Policlinico Universitario Agostino Gem…
NCT07205172 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The periodontal phenotype influences treatment outcomes across dental specialties, as tissues of different thickness respond differently to chemical, bacterial, and mechanical insults. In pediatric patients, understanding the gingival phenotype is particularly relevant: a thin phenotype may predispose to dehiscence, fenestration, and gingival recession-especially at the mandibular incisors-when tooth movement exceeds the biological limits of the bony housing. During the mixed dentition phase, significant changes in soft and hard tissues affect tooth position and periodontal stability, making early phenotype assessment essential. Interceptive orthodontics can reduce the long-term risk of mucogingival defects; early identification of a thin biotype allows for preventive strategies, including soft tissue grafting before critical orthodontic movements. No studies have examined the associat

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📋 Eligibility rules (as published)
Inclusion Criteria: * Pediatric patients attending the Pediatric Dentistry and/or Orthodontics clinic (consultation and/or outpatient appointment). * Parents and/or legal guardians have signed the informed consent for participation in the study. * Age between 5 and 16 years. * Clinical dentition criteria by group: Group 1 (Primary Dentition): Presence in the mandibular arch of deciduous teeth from canine to canine. Group 2 (Early Mixed Dentition): Presence in the mandibular arch of at least two permanent mandibular incisors, fully erupted (incisal edge at occlusal level) or partially erupted (≥50% of the crown), with no clinical attachment loss, and healthy gingiva or mild gingivitis (Gingival Index, GI ≤ 1). Group 3 (Late Mixed Dentition): Presence in the mandibular arch of all four permanent mandibular incisors fully erupted (incisal edge at occlusal level), with no clinical attachment loss, and healthy gingiva or mild gingivitis (GI ≤ 1). Group 4 (Permanent Dentition): Presence in the mandibular arch of all four permanent mandibular incisors fully erupted (incisal edge at occlusal level), with no clinical attachment loss, and healthy gingiva or mild gingivitis (GI ≤ 1). Exclusion Criteria: Patient-related: * Parents and/or legal guardians have not signed the informed consent. * Patients who are not sufficiently cooperative to allow a routine dental examination. * Non-cooperative patients, including those with special needs. * Children with systemic diseases or undergoing medication that affects gingival tissues. * Patients who have already undergone orthodontic treatment or are currently undergoing orthodontic treatment. Tooth-related: * Presence of dental agenesis or dental anomalies. * Dental sites with mucogingival problems.
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What it tests

  • Orthodontic and periodontal analysis
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Where

1 site
Clinica Odontostomatologica - Fondazione Policlinico IRCSS A. Gemelli
Roma, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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