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EIT-guided PEEP Titration Versus Standard Ventilation in Bariatric Surgery

RecruitingNAAges 18 Years - 65 YearsAllJianbo Wu
NCT07207772 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study is a prospective, single-center, single-blind, randomized controlled clinical trial. Patients scheduled for laparoscopic bariatric surgery will be selected and randomly assigned to either the EIT-guided individualized PEEP group (Group P-eit) or the control group (Group P-8). Group P will be ventilated using the PEEP value determined by EIT, while Group C will be ventilated with a fixed PEEP value of 8 cmH2O.The primary outcome is the incidence of postoperative pulmonary complications (PPCs) within 72 hours after surgery.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age between 18 and 65 years; 2. Plan to receive laparoscopic bariatric surgery under general anesthesia; 3. American Society of Anaesthesiologists (ASA) physical status I-III; 4. BMI between 30 and 55 kg/m2; 5. Voluntary participation in this study and signing of an informed consent form. Exclusion Criteria: 1. History of smoking or previous thoracic surgery; 2. Invasive mechanical ventilation within 30 days; 3. Pregnancy; 4. Allergy to EIT electrodes; 5. Persistent hemodynamic instability or refractory shock; 6. Severe cardiopulmonary disease (e.g., severe COPD (Chronic obstructive pulmonary disease), NYHA (New York Heart Association) Class III or IV, acute coronary syndrome, or sustained ventricular tachycardia); 7. Severe pulmonary hypertension (systolic pulmonary artery pressure \>40 mmHg); 8. Increased intracranial pressure, intracranial injury/tumor, or neuromuscular disorders; 9. Conversion to laparotomy; 10. Planned transfer to intensive care unit after surgery.
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What it tests

  • Group P-eit
  • Group P-8
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Where

1 site
The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital
Jinan, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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