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Percutaneous Blockade of the Stellate Ganglion in Electrical Storm

RecruitingPhase 4Ages 18 Years - anyAllUniversity of Sao Paulo General Hospital
NCT07211347 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

There is no randomized clinical study in the literature that evaluated the efficacy and safety of the stellate ganglion infiltration procedure in patients with electrical storm. So far, case reports and retrospective studies suggest that such a strategy should be considered in cases refractory to initial therapy. In this scenario, the European and American guidelines for the treatment of ventricular arrhythmias recommend autonomic modulation in this setting, but only with a level of recommendation IIb (1,2). This project aims to evaluate the effect of stellate ganglion infiltration in patients with electric storm refractory to initial clinical measures. It is a randomized clinical trial where patients will receive treatment with a lidocaine and bupivacaine anesthetic solution or no intervention. The effect of the intervention will be considered positive when there is a reduction of arrhy

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients over 18 years old with structural heart disease and a diagnosis of refractory electrical storm, or those who require discontinuation of antiarrhythmics due to adverse events or contraindications to standard therapy. Exclusion Criteria: * Patients under 18 * History of heart transplant or prior cardiac denervation surgery * Anatomical contraindications for the procedure (prior neck surgery, burns, large scars, or thyroid goiter). * Genetically related polymorphic VT * End-stage renal disease on dialysis
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What it tests

  • Stellate Ganglion Block
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Where

1 site
Clinical Research Center of the Heart Institute - University of São Paulo
São Paulo, Brazil
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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