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โ† Trials
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Acute Cryotherapy on Musculoskeletal Function and Biomarkers

RecruitingNAAges 18 Years - 30 YearsAllUniversity of Texas, El Paso
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In plain words

What the trial is, and whether it could suit you

In 2020, Dubois and Esculier proposed a paradigm shift in the acute management of musculoskeletal injuries, advocating for the transition from the traditional PRICE protocol- Protect, Rest, Ice, Compression, Elevation-to the more holistic PEACE \& LOVE framework. This updated model emphasizes Protection, Elevation, Avoiding anti-inflammatories, Compression, and Education, followed by Load, Optimism, Vascularization, and Exercise. Notably, the PEACE \& LOVE approach omits the use of ice, a decision that has sparked considerable debate. While the rationale centers on avoiding interference with the natural inflammatory and regenerative processes, this omission stands in contrast to a substantial body of animal research suggesting that cryotherapy can mitigate secondary tissue injury by reducing inflammation and metabolic activity. Despite its widespread clinical use, human studies have yet

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * apparently healthy * normotensive * non-smokers (all tobacco products including e-cigarettes) Exclusion Criteria: * Cardiovascular diseases (including hypertension) * pregnancy * any musculoskeletal injury 6 months prior the study
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What it tests

  • Cryotherapy
  • Eccentric exercise-induced muscle damage
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Where

1 site
The University of Texas at El Paso, Rehabilitation Sciences Complex
El Paso, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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