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โ† Trials
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Nutritional Intervention for Constipation Symptoms in Patients With Parkinson's Disease

RecruitingNAAges 18 Years - anyAllHospital de Clinicas de Porto Alegre
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to evaluate whether a dietitian-guided nutritional intervention can improve constipation symptoms in people with Parkinson's disease (PD). The main questions it aims to answer are: * Can a dietitian-guided nutritional intervention increase the number of weekly bowel movements in individuals with PD and functional constipation? * Can this intervention positively influence gut microbiota composition, dietary intake, and nutritional status? Researchers will compare the intervention group to a control group that will receive general dietary guidance only after the study period, to see if the intervention leads to improvements in bowel function and related health outcomes. Participants will: * Follow a diet plan developed by a dietitian, based on dietary reference intakes and tailored to the needs of individuals with PD and constipation * Participate in

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Adults with a previous diagnosis of Parkinson's disease * On a stable dose of levodopa for at least 3 months * Diagnosis of Functional Constipation by the Rome IV protocol Exclusion Criteria: * Diagnosis of atypical or secondary parkinsonism * Hoehn and Yahr stage greater than 2 * Presence of severe neurological or psychiatric disorders that impair the ability to participate in study procedures * Previous diagnosis of dementia * Presence of comorbidities such as active cancer, chronic obstructive pulmonary disease (COPD), heart failure, and/or chronic kidney disease * History of gastrointestinal cancers, inflammatory bowel diseases, or surgeries involving the gastrointestinal tract * Constipation secondary to clinical conditions such as hypothyroidism or diabetes mellitus * Use of opioids * Use of probiotics or antibiotics in the past 8 weeks * Continuous use of laxatives in the past 8 weeks * Presence of severe dysphagia according to the Functional Oral Intake Scale (FOIS) * Individuals receiving enteral or parenteral nutrition * Individuals under nutritional follow-up in the past 3 months
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What it tests

  • Dietitian-Guided Nutritional Intervention
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Where

1 site
Hospital de Clรญnicas de Porto Alegre (HCPA)
Porto Alegre, Brazil
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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