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Follicular Fluid microRNAs in Ovarian Aging and Reproduction

Recruitingn/aAges 18 Years - anyFemaleUniversity of Central Florida
NCT07214246 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to investigate the role of exosomal microRNAs (miRNAs) in follicular fluid (FF) as biomarkers of ovarian aging and predictors of in vitro fertilization (IVF) outcomes. The goal is to identify noninvasive molecular markers that correlate with oocyte quality and reproductive potential, particularly in women of advanced maternal age.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Women undergoing IVF treatment due to male factor infertility or nonovarian causes. * Age groups: younger women \<31 years and older women \>38 years. * Regular menstrual cycles. * Willing and able to provide informed consent. Exclusion Criteria: * Minors (under 18 years) and women aged 32-37 years * Diagnosis of polycystic ovarian syndrome (PCOS). * History of recurrent pregnancy loss. * Presence of endometriosis. * Diagnosis of ovarian insufficiency. * Metabolic disorders (e.g., diabetes). * History of ovarian surgery or chemotherapy. * Any condition that might impact follicular fluid quality or IVF outcomes.
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What it tests

  • No Interventions
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Where

1 site
University of Central Florida
Orlando, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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