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Effects of a 5-Week Probiotic Supplementation Intervention on Markers of Delayed Onset Muscle Soreness

RecruitingNAAges 18 Years - 30 YearsAllUniversity of Minnesota
NCT07219498 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to evaluate how probiotic supplementation (PS) influences post-exercise recovery in healthy, physically active young adults. Researchers aim to determine if the Lactobacillus casei probiotic strain reduces symptoms of delayed onset muscle soreness (DOMS) based on perceived muscle soreness, pressure pain threshold, and power output following exercise induced muscle damage (EIMD).

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📋 Eligibility rules (as published)
Inclusion Criteria: * complete a minimum of 150 minutes a week of at least moderate intensity exercise in either an endurance-based or resistance-based training style based on a self-reported physical activity over the past month * good general health with no injuries or health conditions that would affect physical activity * willing to abstain from consistent NSAID use and other probiotic supplements over the course of this study Exclusion Criteria: * known musculoskeletal injuries or physical limitations that could interfere with performing the designated physical activity required * underlying conditions that could place them at an increased risk during exercise such as cardiovascular, respiratory, or metabolic diseases * currently take a probiotic supplement, are prescribed and taking an antibiotic during the intervention, or report using NSAIDs or steroids within the recovery time window * report using an NSAID more than twice a week on a regular basis
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What it tests

  • Lactobacillus casei
  • Placebo Capsule(s)
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Where

1 site
University of Minnesota
Minneapolis, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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