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Intervention for Communication Quality of Life in Primary Progressive Aphasia

RecruitingNAAges 40 Years - anyAllMaya Henry
NCT07219680 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn whether a personalized, multi-component, virtual speech language treatment program can improve communication and quality of life for adults with primary progressive aphasia (PPA) and their primary communication partners. The study will enroll participants who speak English and/or Spanish. The main questions the study aims to answer are: * Is the telerehabilitation program feasible and acceptable for people with PPA and their study partners? * Do participants with PPA and study partners find treatment beneficial? * What patterns of treatment response are seen in participants? * Which outcome measures are most useful for evaluating changes in communication and quality of life? Researchers will compare participants who receive intervention immediately to participants assigned to a waitlist control group (who will receive treatment after a delay

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📋 Eligibility rules (as published)
Inclusion Criteria for Persons with PPA: * A PPA (Gorno-Tempini et al., 2011) or "PPA-plus" (Mesulam et al., 2001) diagnosis * MMSE score of 15 or higher and must be able to produce single monosyllabic words intelligibly * Must speak English, Spanish or both languages (i.e., bilingual speakers of English or Spanish) * Hearing and vision adequate for participation in teleconference meetings * Must have a study partner available (someone who will commit to attending teleconference sessions, as needed, during assessment and treatment phases) Inclusion criteria for Care Partners: * Partners must express willingness to attend and participate in assessment and treatment sessions, including those targeting dyadic communication goals * Partners must speak English, Spanish or both languages (i.e., bilingual speakers of English or Spanish) * Partner's hearing and vision should be adequate for participation in teleconference meetings The participant and/or study partner must have basic experience using a computer. Exclusion criteria for persons with PPA: * Other central nervous system or medical diagnosis that can account for symptoms * Psychiatric diagnosis that can account for symptoms
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What it tests

  • Multicomponent Lexical Retrieval Cascade Training
  • Multicomponent Video Implemented Script Training in Aphasia
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Where

1 site
University of Texas
Austin, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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