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Sodium vs Potassium Education to Improve Vascular Health

RecruitingNAAges 18 Years - 45 YearsAllFlorida State University
NCT07221448 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to determine if a self-selected high potassium diet is easier to achieve and more effective at improving vascular health than a low sodium diet in generally healthy young adults who typically consume more than the recommended amount of sodium. The main questions it aims to answer are: 1. Is it easier for young adults to increase their potassium intake, rather than reduce their sodium intake? 2. Is a self-selected high potassium diet better at improving vascular health compared to a self-selected low sodium diet? Researchers will compare the effectiveness of an education-based intervention centered only on increasing dietary potassium intake against an education-based intervention centered only on reducing dietary sodium intake. Participants will be randomly assigned to receive comprehensive dietary education on adopting either a high-potassium diet o

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📋 Eligibility rules (as published)
Inclusion Criteria: * Willing and able to attend in-person laboratory visits * Usual sodium intake ≥3,000 mg/d for females and ≥4,000 mg/d for males * Usual potassium intake ≤2,500 mg/d in females and ≤3,000 mg/d in males Exclusion Criteria: * BMI ≥35 kg/m2 * Seated blood pressure ≥130/80 mmHg * Current diagnosis or history of diabetes, renal disease, cancer, cardiovascular disease, or major cardiovascular event (e.g. heart attack or stroke) * Current or recent use of a diuretic (within the past 6 months) * Elevated blood lipids (LDL cholesterol ≥190 mg/dL) * Elevated serum potassium level (\>5.1 mmol/L) * Elevated BUN (\>22 mg/dL) * Elevated creatinine (\>1.2 mg/dL) * Low eGFR (\<90 mL/min/1.73 m²) * Current or recent use of tobacco, nicotine, or illicit drugs * Radical hysterectomy or oophorectomy (females)\* * Pregnant or lactating * Following a weight-loss diet, or intending to gain or lose weight during the study period
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What it tests

  • High potassium dietary education/counseling
  • Low sodium dietary education/counseling
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Where

1 site
Florida State University
Tallahassee, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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