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Recovery of Physical Function After Critical Illness In Older Adults

Recruitingn/aAges 18 Years - 99 YearsAllUniversity of Kentucky
NCT07225257 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The proposed study is a prospective, observational study assessing the recovery of muscle and physical function in patients surviving critical illness (n =150) at hospital discharge (baseline) and repeated serially. Patients will be enrolled after life-saving modalities have been weaned near hospital discharge. Patients will participate in testing at baseline, 3-, 6-, 12-, and 24-months after hospital discharge. In a subset of patients (n = 18), muscle biopsies will be performed at baseline and then repeated once at either 12- or 24-months after hospital discharge.

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📋 Eligibility rules (as published)
Inclusion Criteria: * adult patients (≥40 years of age) * patients who have survived an ICU admission of at least 72 hours * diagnosis of acute lung injury or sepsis are eligible. Exclusion Criteria: * individuals who were not ambulatory prior to ICU admission, * not expected to survive at least 6 months, * have a new or pre-existing brain infarct, injury, or neurological condition with deficits preventing participation in physical testing, * have a pre-existing geriatric syndrome that were confound recovery trajectory
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What it tests

  • Not listed
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Where

1 site
University of Kentucky, Lexington, Kentucky 40536
Lexington, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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