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Hormonal Optimization: Late vs. Immediate Start After Discontinuation of Oral Contraceptives in Assisted Reproductive technologY (HOLIDAY)

RecruitingNAAges 18 Years - 40 YearsFemaleShady Grove Fertility Reproductive Science Center
NCT07225660 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

HOLIDAY is a two-arm, parallel-group, multi-center, randomized trial in which subjects undergoing planned oocyte cryopreservation will be randomized to receive either a 2-month pause of Combined Hormonal Contraceptives (CHC) or immediate start (without a pause).

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Ovary-bearing individuals 18 to 40 years of age. 2. BMI \< 40 kg/m2 3. Non-smoker for at least 3 months prior to study enrollment. Exclusion Criteria: 1. BMI greater than or equal to 40 kg/m2 2. Current Smoker 3. Any contraindications to ovarian stimulation or outpatient egg retrieval under anesthesia
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What it tests

  • OCP pause
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Where

3 sites
Yale Fertility Center
Orange, United States
Shady Grove Fertility Rockville
Rockville, United States
Reproductive Medicine Associates of New York
New York, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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