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A First-in-Human Study of MEN2501 in Participants With Platinum-Resistant Ovarian Cancer

RecruitingPhase 1Ages 18 Years - anyFemaleStemline Therapeutics, Inc.
NCT07226427 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a first-in-human, open-label, dose-escalation, dose-optimization trial designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and antitumor activity of MEN2501 monotherapy in adult participants with platinum-resistant ovarian cancer.

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📋 Eligibility rules (as published)
Key Inclusion Criteria: * Participants must have a histopathologically confirmed diagnosis of high-grade serous ovarian cancer, primary peritoneal cancer, or fallopian tube cancer. Key Exclusion Criteria: * Participants with primary platinum-refractory disease. Note: Other protocol-defined inclusion/exclusion criteria may apply.
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What it tests

  • MEN2501
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Where

15 sites
Highlands Oncology Group
Springdale, United States
Yale University
New Haven, United States
Florida Cancer Specialists & Research Institute
Sarasota, United States
Massachusetts General Hospital
Boston, United States
Karmanos Cancer Institute
Detroit, United States
Mayo Clinic
Rochester, United States
NEXT Virginia
Fairfax, United States
Icon Cancer Centre
South Brisbane, Australia

…and 7 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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