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Open Pilon With FIBERGRAFT AERIDYAN Matrix Bioactive Glass

Recruitingn/aAges 18 Years - anyAllUniversity of Missouri-Columbia
NCT07227493 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Open pilon fractures are challenging problems to manage. Infection rates vary from 6-30% and metaphyseal nonunion varies from 7-20%. The current recommendation for the management of open pilon fractures with bone loss is a staged approach, with internal fixation around an antibiotic spacer. Fibergraft Aeridyan Bone Graft Matrix is currently used along with other forms of allograft at our institution for filling bone voids in open pilon fractures. This is a prospective, observational study looking at the use of Fibergraft Aeridyan bone graft matrix and its efficacy in open pilon fractures. Everything in this study will be according to the standard of care at our institution other than two research only CT scans. One will be performed at the patient's 6-month visit and the other will be performed at the patient's 12-month visit. The investigators hypothesize that Fibergraft Aeridyan Bone G

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📋 Eligibility rules (as published)
Inclusion Criteria: * 18 years of age or older * Open pilon fracture requiring bone grafting * Able to provide informed consent for the study prior to definitive care Exclusion Criteria: * Under 18 years of age * Open pilon fracture not requiring bone grafting * Receiving definitive care at an outside facility * Unlikely to make follow-up appointments * Active infection at the time of definitive care * Unable to provide informed consent prior to definitive care * Prisoners * Pregnant patients
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What it tests

  • Fibergraft Aeridyan Matrix
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Where

1 site
University of Missouri - Columbia
Columbia, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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