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High Intensity Alternating Current Stimulation as a Neuromodulation Therapy for Alcohol Use Disorder: A Pilot Study

RecruitingNAAges 18 Years - 60 YearsAllShanghai Mental Health Center
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In plain words

What the trial is, and whether it could suit you

This one-arm pilot study aims to evaluate the preliminary clinical, behavioral, and neurophysiological effects of high-intensity transcranial alternating current stimulation (HI-tACS) in individuals with alcohol use disorder (AUD). Participants will receive HI-tACS and undergo clinical and neurophysiological assessments before and after the intervention.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Education level of junior high school or above, capable of completing questionnaires and behavioral tests; * Aged 18-60 years; * Meet DSM-5 diagnostic criteria for Alcohol Use Disorder; * No abnormal findings on physical examination; * Agree to participate in follow-up assessments; * No contraindications for MRI scanning. Exclusion criteria: * Have impaired intelligence (Intelligence Quotient\<70); * Prior tDCS or TMS treatment within the past 3 months; * Contraindications for TMS therapy (e.g., intracranial metal implants, history of traumatic brain injury, skull defects, cardiac pacemakers, cardiovascular diseases, or epilepsy); * Severe somatic diseases or major organ dysfunction; * Psychiatric disorders per DSM-5 criteria (e.g., schizophrenia, schizoaffective disorder, intellectual disability, autism spectrum disorder, dementia, memory impairment, or other cognitive disorders). * Psychiatric disorders per DSM-5 criteria (e.g., schizophrenia, schizoaffective disorder, intellectual disability, autism spectrum disorder, dementia, memory impairment, or other cognitive disorders). * Diagnosis of other substance-related and addictive disorders or behavioral addictions.
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What it tests

  • HI-tACS
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Where

1 site
Shanghai Mental Health Center
Shanghai, China
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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