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Effects of Moderate/Severe Traumatic Brain Injury in the Subacute or Chronic Phase on Locomotor Strategies Involved in Navigation in Complex Virtual Environments

RecruitingNAAges 18 Years - 55 YearsAllPôle Saint Hélier
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In plain words

What the trial is, and whether it could suit you

While clinical assessment of locomotor function in this population is carried out using tasks involving walking in a straight line without any obstacles, it does not take into account ecological situations (i.e., situations comparable to real-life situations) in which the person interacts with their environment, such as walking down a street with other pedestrians, which is fundamental to everyday life. This research therefore aims to study the social navigation skills during locomotion of people who have suffered a moderate or severe head injury in the chronic phase in more ecological tasks. This will provide a better understanding of the difficulties encountered by these patients during locomotor interactions in everyday life.

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria for Traumatic Brain Injury group : * 18 ≤ Age ≤ 55 years old * Male/female * Having suffered a first non-penetrating head injury * Moderate to severe severity with initial Glasgow Coma Scale score 5\<GCS\<13 * In the subacute or chronic phase (≥ 3 months at the date of the experiment, relative to the date of the injury) * Able to walk (10WMT speed ≥ 0.8 m/s, able to walk at least 20 m without technical or human assistance, PM ≥ 300 m) * Able to maintain dynamic balance while standing (TUG\<16s) * Able to answer simple questionnaires, according to the investigator's judgment * Having given their free, informed, expressed (written) consent * Registered with a social security system * Individuals under legal protection measures such as guardianship may be eligible Inclusion Criteria for healthy control group : * 18 ≤ Age ≤ 55 years old * Male/female * Able to walk (≥ 0.8 m/s, able to walk at least 20 m without technical or human assistance, PM ≥ 300 m) * Able to answer simple questionnaires, according to the investigator's judgment * Having given free, informed, expressed (written) consent * Registered with a social security system Exclusion Criteria specific to patients in the traumatic brain injury group : \- Person under legal protection (excluding guardianship) or unable to express consent Exclusion Criteria for both groups : * Severe patho-psychiatric care underway, which may impact the conduct of the protocol, at the investigator's discretion * Presence of neurological signs suggestive of a neurodegenerative disease responsible for gait disturbance (Parkinson's syndrome, Alzheimer's disease, etc.) * Individuals with musculoskeletal disorders that impact their locomotor abilities * Presence of uncontrolled epilepsy at the time of inclusion * Presence of visual impairments that make experimentation impossible, at the discretion of the investigator * Pregnant, parturient, or breastfeeding women * Participants in another ongoing research protocol involving human subjects Exclusion Criteria for healthy control group : * Presence of fatigue, trauma, or a condition affecting mobility, posture, balance, or walking * Persons deprived of their liberty by a judicial or administrative decision * Persons deprived of their liberty by judicial or administrative decision * Persons under legal protection (guardianship, curatorship, judicial protection) or unable to express their consent * Persons undergoing severe psychiatric treatment or admitted to a health or social care facility for purposes other than research.
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What it tests

  • Locomotion in a virtual reality setting
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Where

1 site
Fondation Saint Helier
Rennes, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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