AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Anesthesia Management in Endovascular Therapy for Ischemic Stroke - 2

RecruitingNAAges 18 Years - anyAllUniversity Hospital, Clermont-Ferrand
💬

In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn what is the best anesthetic management in participants with severe stroke that require a medical intervention called mechanical thrombectomy (MT) done to open the occluded brain vessel. The main question it aims to answer is: • Is general anesthesia (GA) better than procedural sedation (PS) for improving functional performance and decrease dependance in daily life 3 months after stroke? GA (a non-arousable state induced by anesthetic medications that require respiratory assistance) or PS (a state of reduced arousal induced by lesser dose of anesthetic medications that do not require respiratory assistance) are both used for MT. GA enables strict immobility that could facilitate the conduct of MT but lessen blood pressure and blood flow in the brain. PS provides less drop in blood pressure but MT could be more difficult due to possible moveme

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥18 years * Acute ischemic stroke with an occlusion of the intracranial internal carotid artery and/or the proximal middle cerebral artery (M1-M2) with or without association of extracranial occlusion of the cervical internal carotid artery (tandem lesion) * Eligible for mechanical thrombectomy according to international guidelines * Informed and signed consent of patient, or if he is unable to consent the consent of patient's relative or emergency procedure in the absence of relative * National health insurance Exclusion Criteria: * Coma or altered vigilance defined as a score ≥ 2 on the level of consciousness 1A subscale of the NIHSS * Premorbid disability defined as a mRS \> 2 * Posterior circulation stroke * Associated cerebral hemorrhage * Stroke complicating another acute illness or postoperative stroke * Emesis at arrival in angiosuite * Allergy to anesthetic medication * Pregnant or breast-feeding women * Adult under the protection of the law
💊

What it tests

  • General Anesthesia
  • Procedural sedation
📍

Where

16 sites
Le Centre Hospitalier Universitaire d'Angers
Angers, France
Le Centre Hospitalier Universitaire Morvan de Brest de Brest
Brest, France
CHU de Clermont-Ferrand
Clermont-Ferrand, France
Le centre hospitalier universitaire de Lille
Lille, France
Les Hospices Civils de Lyon
Lyon, France
L'Assistance Publique - Hôpitaux de Marseille
Marseille, France
Le centre hospitalier universitaire de Montpellier
Montpellier, France
Le Centre Hospitalier Universitaire de Nantes
Nantes, France

…and 8 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy