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DEXDES Trial: Dexmedetomidine-Desflurane Combination in Laparoscopic Colectomy

RecruitingNAAges 18 Years - 65 YearsAllTam Anh Research Institute
NCT07239479 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This randomized double-blind controlled clinical trial aims to evaluate the efficacy and safety of combining Dexmedetomidine with Desflurane in patients undergoing elective laparoscopic colectomy. The study will assess whether the combination can reduce Desflurane consumption, improve intraoperative hemodynamic stability, and enhance postoperative recovery compared to Desflurane alone.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18-65 years * ASA Physical Status I-II * Elective laparoscopic colectomy * Written informed consent provided Exclusion Criteria: * Severe cardiac, hepatic, or renal disease * COPD or bronchial asthma * Chronic opioid or psychotropic medication use * Atrioventricular block (grade II-III), sick sinus syndrome * Significant intraoperative bleeding or hemodynamic instability
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What it tests

  • Dexmedetomidine + Desflurane
  • Desflurane + Normal Saline
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Where

1 site
Tam Anh TP. Ho Chi Minh General Hospital
Ho Chi Minh City, Vietnam
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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