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Supplementary Nerve Blocks Added to the Adductor Canal Block for Postoperative Pain Management in Primary Total Knee Arthroplasty: A Randomized Controlled Comparison of Sciatic, BiFeS, and IPACK Techniques

RecruitingNAAges 18 Years - 75 YearsAllErzincan University
NCT07242170 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Postoperative pain following total knee arthroplasty (TKA) is a significant clinical problem that delays early mobilization, reduces patient satisfaction, and increases analgesic requirements. The adductor canal block (ACB), which aims to provide analgesia while preserving motor function, is widely used in postoperative pain management after TKA. However, clinical and anatomical studies have demonstrated that ACB is effective only in the anteromedial sensory innervation of the knee and does not adequately block pain originating from the posterior knee capsule. This limitation reduces analgesic effectiveness, particularly in patients with a prominent posterior pain component. The sciatic nerve block has long been considered the gold standard for managing posterior knee pain. However, due to disadvantages such as motor weakness and delayed rehabilitation, current pain management protocols

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients classified as American Society of Anesthesiologists (ASA) physical status I-III * Patients undergoing primary total knee arthroplasty * Patients undergoing unilateral total knee arthroplasty * Patients between 18 and 75 years of age Exclusion Criteria: * Patients classified as American Society of Anesthesiologists (ASA) physical status IV or higher * Patients undergoing revision total knee arthroplasty * Patients undergoing bilateral total knee arthroplasty * Patients with neuromuscular disease * Patients who decline to participate in the study * Patients with cognitive dysfunction * Patients with known drug allergies * Patients with a history of local anesthetic systemic toxicity * Patients with neurological dysfunction * Patients with bleeding diathesis * Pregnant patients
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What it tests

  • Adductor canal block
  • BiFeS Block (Biceps Femoris Short Head Block)
  • IPACK block
  • Sciatic Nerve Block
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Where

1 site
Erzincan Binali Yıldırım Üniversitesi
Erzincan, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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