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Study Evaluating the Impact of Using Triplex Rapid Diagnostic Tests (SARS-CoV-2/Influenza/RSV) on Antibiotic Prescribing

RecruitingNAAges 1 Year - anyAllAssistance Publique - Hôpitaux de Paris
NCT07243249 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Respiratory infections are very common, especially during winter, and are often caused by viruses such as influenza, SARS-CoV-2 or respiratory syncytial virus (RSV). These illnesses are generally mild, but their symptoms do not always allow a clear distinction to be made between a viral infection and a bacterial infection. In the absence of a precise diagnosis, antibiotics may be prescribed when they are not necessary in many cases. However, the excessive use of antibiotics contributes to the development of bacterial resistance, which is a major public health issue. The aim of this study is to better understand whether the use of a rapid test (called TROD), which can quickly identify certain respiratory viruses, can help doctors reduce unnecessary antibiotic prescriptions for these infections. The test will be performed using a swab gently inserted into the nose.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age ≥ 1 year 2. Presenting with: * Either fever (temperature \> 38°C measured by patient or physician) within the past 72 hours, and one of the following symptom combinations: 1. Rhinorrhea (white, yellow, or green discharge) and/or nasal obstruction, and cough 2. Body aches, cough, and fatigue 3. Odynophagia and negative strepto-test 4. Cough 5. Otalgia * Or suspicion of lower respiratory tract infection: signs of infection (respiratory rate \> 20/min, heart rate \> 100/min, fatigue, Body aches, chills, or fever), associated with pulmonary localization signs \[cough, sputum, chest pain, auscultatory abnormality (rhonchi, crackles, or wheezing)\] 3. Affiliation with the national health insurance system 4. Informed consent obtained from the adult participant, or from the person(s) with parental authority for a minor participant Exclusion Criteria: 1. Requirement for hospitalization 2. Presence of a non-respiratory infection requiring concomitant antibiotic treatment. 3. Patients covered by State Medical Aid (AME)
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What it tests

  • TROD
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Where

1 site
Assistance Publique - Hôpitaux de Paris
Garches, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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