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Reducing the Burden of Cardiovascular Events With Antiplatelet Therapy in Patients With IntraCerebral Haemorrhage

RecruitingPhase 3Ages 18 Years - 99 YearsAllChristian Medical College and Hospital, Ludhiana,…
NCT07243704 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

BEAT ICH will be a pragmatic, randomised, placebo-controlled, blinded, superiority clinical trial aiming to recruit 5676 patients aged ≥18 years who survive ICH and assign them 1:1 to starting antiplatelet monotherapy (Aspirin 75 mg od) versus placebo for the entire duration of the trial for preventing MACE. Recruitment duration is for 2.5 years. The duration of the medication and follow-up will vary based on recruitment timeline. If recruited during the first year of the trial, the patient will take the medication for three years or until the trial ends or an event occurs, with a matching follow-up period. If recruited towards the end of the trial, he/she will take the medication for six months and be followed up for the same duration. The trial's follow-up duration is three years. The patients will be recruited for 2.5 years, and the last recruit will have a minimum follow-up of six mo

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥18 years * First-ever Intracerebral Haemorrhage * Presenting ≥24 hrs up to 3 months of stroke symptoms confirmed by brain imaging * CT /MRI confirming Intracerebral Haemorrhage * Alive ≥24 hours after non-traumatic ICH Exclusion Criteria: * ICH is known to be due to trauma, a structural cause (e.g., aneurysm, arteriovenous malformation, cerebral cavernous malformation, venous thrombosis, or tumour), or haemorrhagic transformation of cerebral infarction * Glasgow coma score ≤5 * Taking any antiplatelet or anticoagulant therapy 15 days prior to randomization. * Women pregnant, breastfeeding, childbearing potential, and not using contraceptives * Enrolled in any other clinical trial * Sick or compromised patients with life expectancy of less than a year * Geographical or other factors that prohibit long-term follow-up
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What it tests

  • Aspirin 75 mg daily
  • Placebo
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Where

33 sites
Government General Hospital
Guntur, India
Lalitha Super Specialty Hospital
Guntur, India
Dr Ramesh Cardiac and Multispecialty Hospital
Guntur, India
Government General Hospital
Kākināda, India
Narayana Medical College and Hospital
Nellore, India
Apollo Excelcare Hospitals
Guwahati, India
Baptist Christian Hospital
Tezpur, India
All India Institute of Medical Science
Patna, India

…and 25 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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