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Supplementation With Sirtuin Activators in Women With Increased Body Weight

RecruitingNAAges 40 Years - 65 YearsFemalePoznan University of Life Sciences
NCT07245979 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn if the six-month supplementation with sirtuin activators can affect metabolism in 40-to-65-year old women with increased body weight. The main questions it aims to answer are: Does sirtuin activators affect lipid and carbohydrate metabolism? Does sirtuin activators affect oxydative stress, immune functions and cell ageing? Researchers will compare sirtuin activators to a placebo (a look-alike substance that contains no drug) to see if drug sirtuin activators works to improve metabolic status. Participants will: Take sirtuin activators or a placebo every day for 6 months. Visit the university once every 3 months for checkups and tests.

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📋 Eligibility rules (as published)
Inclusion Criteria: * females * age: 40-65 years * overweight or obese: BMI \>25 kg/m2 Exclusion Criteria: * males * BMI \< 25 kg/m2 * sirtuin activators administration for 3 months prior to study * pregnancy or breastfeeding * recent dieting or being on calorie restricted diet * receiving pharmacotherapy to treat obesity, diabetes or hyperlipidemia * post-bariatric surgery * diabetes * cancer * chronic kidney, liver or autoimmune diseases * alcohol addiction
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What it tests

  • Sirtuin activators
  • Placebo
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Where

1 site
Poznan University of Life Sciences
Poznan, Poland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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