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Targeting Neuroplasticity for Persistent Post-Concussive Cognitive Symptoms

RecruitingNAAges 18 Years - 65 YearsAllUniversity of Minnesota
NCT07246993 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This project investigates an innovative combination of non-invasive neuromodulation (transcranial direct current stimulation - tDCS) and cognitive training as a novel treatment approach aimed at improving function in individuals suffering from persistent post-concussive syndrome (PPCS) following mild traumatic brain injury (mTBI).

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18-65 * Has sustained a single mTBI 3-12 months prior to enrollment * Meets criteria for PPCS (assessed using the CP Screen) * Has reliable access to a smartphone Exclusion Criteria: * Inability to provide informed consent or complete study procedures * History of moderate/severe TBI * Significant neurological or psychiatric disorders (other than PPCS-related symptoms like mild depression/anxiety) * Substance dependence within the last six months * Contraindications to tDCS (e.g., implanted metal, skin lesions on scalp)
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What it tests

  • Active tDCS
  • Sham tDCS
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Where

1 site
University of Minnesota
Minneapolis, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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