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Effect of Instrumentation Kinematics on Intraoperative and Post-operative Pain in Maxillary Premolars With Acute Irreversible Pulpitis

RecruitingNAAges 20 Years - 50 YearsAllAl-Azhar University
NCT07250399 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Post-endodontic pain refers to the discomfort experienced following endodontic procedures. The incidence of post-operative pain is reported to be 25-40% regardless of the pulp and periradicular condition. It has been shown that pain prevalence declined from 40% in the first 48 h after treatment to 11% 7 days post-treatment. The mechanisms behind post-endodontic pain are complex and multifactorial that include host-dependent factors such as host immunity and preoperative pain history as well as operator-related factors such as chemical, mechanical or bacterial injury that occurs during endodontic procedure. A major contributor to this pain is the extrusion of infected debris as dentin chips, microorganisms, and the remnants of pulp tissue to the periradicular area. The intensity of pain is directly proportional to the extent of tissue injury caused. During root canal preparation, a varie

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📋 Eligibility rules (as published)
Inclusion Criteria: * Maxillary first and second bi-rooted premolar teeth having type I root canal. * have mature teeth with closed apex. * Teeth with prolonged response to the pulp tests. * Spontaneous pain (preoperative visual analog scale score )4-6). * Teeth with normal periapical appearance. * Restorable teeth. * Patients who will be able to understand the informed consent form and pain recording scales used in the study will be included. Exclusion Criteria: \-
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What it tests

  • EdgeOne Fire reciprocating system
  • JZ file system
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Where

1 site
from the outpatient clinic of Endodontic Department, Faculty of Dental Medicine for Girls, Al-Azhar University
Cairo, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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