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Comperative Effects of Transcutaneous Auricular and Cervical Vagus Nerve Stimulation in Subacute Stroke Patients

RecruitingNAAges 45 Years - 70 YearsAllLahore University of Biological and Applied Scien…
NCT07253870 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to determine whether transcutaneous vagus nerve stimulation (tVNS) via auricular or cervical branches enhances recovery when combined with task-specific training in subacute stroke patients. We anticipate finding that both stimulation methods may improve upper limb motor function compared to conventional therapy. The research is expected to reveal specific cognitive domains (attention, memory, executive function) that benefit most from each stimulation approach, while also demonstrating meaningful improvements in patients' quality of life measures. These findings may make a significant practical contribution by providing clinicians with evidence-based guidance on suitable tVNS approach for improving functional independence and quality of life for stroke survivors.

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📋 Eligibility rules (as published)
Inclusion Criteria: * First ever ischemic stroke * Subacute phase of stroke 3-6 months post onset * Fugl-Meyer Assessment-Upper Extremity (FMA-UE) scores ranged from 20 - 50 Exclusion Criteria: * Previous injury or surgical intervention of vagus nerve * Patients with cardiac arrest and arrythmias * Uncontrolled hypertension * Apraxia * Other neurologic or musculoskeletal diseases * Presence of implanted electronic devices
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What it tests

  • Transcutaneous vagus nerve stimulation through auricular branch along with task specific exercises
  • Transcutaneous vagus nerve stimulation through cervical branch along with task specific exercises
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Where

1 site
Shadman Medical Center, Stroke Rehabilitation
Lahore, Pakistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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