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Distribution Characteristics of Helicobacter Pylori

Recruitingn/aAges 18 Years - 80 YearsAllJilin University
NCT07253948 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aimed to analyze the distribution characteristics of Helicobacter pylori（H. pylori） in varying stages of atrophic gastritis and early gastric cancer using immunohistochemical staining, with the goal of providing guidance for the early screening of gastric cancer. A retrospective analysis was conducted on gastric biopsy cases that underwent H. pylori immunohistochemical staining at our center from March 1, 2023, to August 15, 2025. Cases were classified into non-atrophic and atrophic groups based on the presence or absence of gastric atrophy. All cases were further divided into non-open and open atrophy groups and additionally into early gastric cancer and non-cancer groups. The distribution of H. pylori across subgroups was compared, and multivariate analyses were performed to identify risk factors associated with the development of early gastric cancer.

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📋 Eligibility rules (as published)
Inclusion Criteria: * age 18-80 years * received H. pylori immunohistochemical testing at our center and tested positive. Exclusion Criteria: * biopsies not collected from both the greater and lesser curvatures of the gastric antrum and body * history of stomach surgery * suspected autoimmune gastritis under endoscopy * liver cirrhosis * severe comorbidities such as advanced cancer or renal failure * advanced gastric cancer or gastric lymphoma
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What it tests

  • immunohistochemical testing
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Where

1 site
the First Hospital of Jilin University
Changchun, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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