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Effect of Calcium-Based Bioceramic Sealer and Resin-Based Sealer on Postoperative Pain

RecruitingNAAges 18 Years - 55 YearsAllFatima Memorial Hospital
NCT07256691 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to compare the effect of calcium-based bioceramic sealer and resin-based sealer on postoperative pain in adult patients with asymptomatic apical periodontitis undergoing root canal treatment. Asymptomatic apical periodontitis is a condition where the tissue around the tip of the tooth root is inflamed or shows a lesion on X-ray, but the patient does not experience pain. A total of 60 patients will be randomly assigned to receive root canal treatment with either the bioceramic sealer (Group A) or the resin-based sealer (Group B). Pain after treatment will be measured using a 0-10 Numeric Pain Rating Scale at 4, 24, and 48 hours post-treatment. The highest pain score reported will determine whether the treatment is considered a success (no or mild/moderate pain) or failure (severe pain). The results of this study will provide evidence on which sealer is associated with le

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📋 Eligibility rules (as published)
Inclusion Criteria:Age 18-55 years. * Both genders. * Teeth diagnosed with asymptomatic apical periodontitis. * Teeth are asymptomatic (no pain on percussion or palpation). * Non-vital pulp (no response on Electric Pulp Testing). * Teeth with fully formed apices. * Teeth with Periapical Index (PAI) scores 2-4 on radiographs. Exclusion Criteria: * Medically compromised patients (e.g., those with immunosuppressive or systemic diseases, or on medications that may affect healing). * Patients who refuse to participate or are unable to communicate their symptoms (e.g., due to psychological disorders). * Teeth where full working length cannot be reached. * Periodontally compromised teeth (probing depth \>4 mm). * Complications during treatment (e.g., separation of a file, ledging). * Overfilling (filling beyond the radiographic apex) or short filling (\>2 mm from the radiographic apex).
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What it tests

  • Resin-based sealer obturation technique
  • Bioceramic sealer obturation
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Where

1 site
Fatima Memorial Hospital
Lahore, Pakistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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